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Nat Rev Drug Discov 10:209-19

The mechanism involves impaired GLUT4 translocation, increased hepatic gluconeogenesis, and reduced insulin receptor sensitivity

E11G0369 has been referenced in the below publications Low Expression of Sirtuin 1 in the Dairy Bovines with Mild Fatty Liver Alters Hepatic Lipid Metabolism

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There are conflicting data regarding the association of this jaundice with increased lipase activity in the breast milk, which results in increased levels of free fatty acids that could inhibit hepatic BGT