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The lead crises in Flint, Michigan, and Newark, New Jersey, an alarming national water study in Canada, and the 2023 discovery of forever chemicals (PFAS) in nearly half of US drinking-water sources have all called into question the safety of North American public water supplies, which had long been considered among the best and most tightly regulated on earth

Oral AOD 9604 formulations exist but have significantly lower bioavailability than subcutaneous injection

An initial consultation establishes injury history, inflammatory markers, and organ function before any protocol is designed

thus, research typically involves its use in an injectable formulation