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The pertinent parameter should be the responsivity of the HPA axis network, as revealed by the magnitude of the cortisol awakening response, or the response to an evoked stress

Its role in preventing megaloblastic anemia was established as early as the 1930s, and by the 1960s, folate supplementation was proposed as a preventive measure against neural tube defects ( NTDs )

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Melatonin, immune function and aging