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Moreover, folate deficiency might contribute to the increased coronary risk associated with the thermolabile MTHFR mutation (Hopkins et al, 1995

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This appears to be related to the accumulation, aggregation, and eventual precipitation in cataractous opacities of damaged proteins

By taking into consideration oligomeric species of Cu(I)-dithiothreitol, the modified calculations conclude affinity values several orders of magnitude higher, an observation that deserves further comments