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The NHS hypokalaemia overview explains why it matters, and clinical references such as StatPearls on B12 deficiency treatment specifically flag monitoring potassium during the early loading phase in people who were severely deficient

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Vitamin B12 deficiency left untreated can lead to serious health complications, including type 2 diabetes and cardiovascular disease

Additionally, certain long-term medicationssuch as antacids or metformincan interfere with B12 absorption