We systematically examine key approaches, such as targeting neuroinflammatory cascades, modulating neurotrophic factors, and mitigating glutamate-mediated excitotoxicity
The Phase 2 trial enrolled participants with obesity and evaluated multiple dose levels over 48 weeks: 1 mg dose: 8.7% average body weight reduction 4 mg dose (escalated from 2 mg): 17.1% average body weight reduction 8 mg dose (escalated from 2 mg): 22.8% average body weight reduction 12 mg dose (escalated from 2 mg): 24.2% average body weight reduction Placebo: 2.1% average body weight reduction Those Phase 2 numbers were striking enough
Andrew Huberman: No, I'm going to try chromat
Adolescents with ADHD and OSA often show phenotypic risk factors including obesity and metabolic syndrome
Begliuomini S, Casarosa E, Pluchino N, Lenzi E, Centofanti M, Freschi L, et al