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And yet, when you ask the question that matters most, what do we actually know in humans, the answer is uncomfortable

These enzymes act cooperatively at different sites in the free radical pathways

10.4049/jimmunol.179.4.2576 67

To resolve this, researchers developed the Glutamic acid-Valine-Citrulline (EVCit) linker by adding an acidic amino acid at the N-terminus (Figure 6b) [5]