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Seetharaman J, Sarma MS (2021) Chelation therapy in liver diseases of childhood: current status and response

Clinical epigenetics

The glutaminase encoded by GLS2 can be directly bound and transcriptionally induced by p53, reducing cellular sensitivity to ROS-associated apoptosis, possibly through glutathione-dependent antioxidant defense (Suzuki et al., 2010

They improve mitochondrial function, reduce reliance on glycolysis, and restore normal metabolic patterns in multiple tissue types

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