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Rockefeller's Birsoy lab has discovered that the antioxidant glutathione plays a vital role in maintaining the smooth operations of a protein-producing hub in the cell called the endoplasmic reticulum by acting as a protein proofreader. Rockefeller has an incredibly rich history of research on the endoplasmic reticulum, so we know that when things go wrong in this organelle, many diseases ranging from neurodegeneration to cancer can result, says Kivan Birsoy

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Conversely, eNOS deglutathionylation can result in eNOS upregulation, maintaining physiological NO levels

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