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Causes of Leaky Gut: Chronic stress, a diet high in processed foods and sugars, excessive alcohol, and certain medications like NSAIDs

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A more comprehensive evaluation of the same cohort using spatial transcriptomics revealed more detailed vascular and immunological features of microvessels in the brain, including serum protein extravasation, platelet accumulation and coagulation system activation 22

A landmark 1991 double-blind, placebo-controlled trial published in The Lancet investigated patients with ME/CFS who exhibited low red blood cell (RBC) magnesium levels

Nobody disputes the biochemistry