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It is quite rare (1:1000) and it is facilitated by some pre-existing risk factors, such as severe head injury, epilepsy, food disorders, arteriovenous malformations, cerebral neoplasms or infections, severe stroke and cerebrovascular disease, concomitant use of other medications that lower the seizure threshold [12]

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California may not see the same surge in demand as other states, because the market is already operational in neighbors Oregon and Nevada

While it is important to be alert to suspicious anogenital lesions, it is also important to perform a correct differential diagnosis, with consideration of conditions including lichen sclerosus et atrophicus, localized vulvar pemphigoid, pinworm infection, scabies, inverse psoriasis, atopic and contact dermatitis, perianal streptococcal dermatitis, and candidiasis